Job Title

Medicinal/synthetic chemistry researcher / Principal Scientist

Responsibilities

• Lead discovery programs focused on conjugates including ADC, PDC, SMDC, and related platforms
• Drive scientific strategy for linker-payload design, conjugation approaches, and molecular optimization
• Design and oversee medicinal chemistry efforts for payloads, linkers, and conjugatable small molecules
• Establish structure-activity relationships (SAR) and guide optimization based on potency, selectivity, PK/PD, and developability
• Contribute to translational and clinical strategy discussions, including indication selection, biomarker considerations, and differentiation opportunities
• Interpret and integrate in vitro/in vivo pharmacology and ADME data to drive decision making
• Manage external collaborations and CRO activities related to medicinal chemistry and conjugate development

Qualifications

• Ph.D. in medicinal chemistry, organic chemistry, pharmaceutical sciences, or related disciplines.
• Mandatory postdoctoral research experience more than 3 years.
• Strong expertise in synthetic organic chemistry and medicinal chemistry strategy.
• Experience with conjugate therapeutics such as ADCs, PDCs, SMDCs, or related modalities.
• Deep understanding of linker-payload chemistry, conjugation technologies, and oncology pharmacology.
• Demonstrated leadership in multidisciplinary drug discovery teams.
• Strong scientific problem-solving and strategic thinking skills.
• Excellent communication and presentation skills.

Benefits & Application QR code in attached file