Are you ready to use your scientific expertise to help transform bold ideas into life-changing medicines? If so, Kaigene could be the right place for you.

At Kaigene, patients come first. We are driven to address unmet medical needs around the world by thinking big, moving quickly, and working together to turn the impossible into reality. If you take initiative, lead with confidence, collaborate naturally, and stay curious about what science can do, you’ll fit right in.

About Kaigene in Rockville, MD

Founded in 2022, Kaigene is a startup dedicated to the discovery and development of innovative medicines using antibody-based technologies. Our mission is to create best-in-class biotherapeutics for patients living with autoimmune disease. Our management team brings deep industry experience and a strong track record in biologics discovery and development.

We consider our employees our most valuable asset and are committed to providing meaningful opportunities to learn, grow, and advance professionally. Kaigene fosters an environment of innovation, open communication, knowledge building, and teamwork—where employees can see the direct impact of their work on the success of the organization.

Job Description

We are seeking a highly motivated and experienced scientist to join our Pharmacometrics and Translational Sciences team. The successful candidate will be responsible for PK/PD modeling, dose selection, and translational strategy across multiple therapeutic modalities including antibodies, conjugates (ADC/DAC/AOC), and peptide/RNA therapeutics.

Key Responsibilities

• Develop and apply PK/PD models to support discovery, preclinical, and clinical-stage programs. 

• Perform translational modeling from in vitro and in vivo data to predict human pharmacokinetics, pharmacodynamics, and efficacious dose ranges. 

• Integrate diverse datasets (e.g., PK, biomarker, efficacy, safety) to inform decision-making. 

• Collaborate with biology, pharmacology, and clinical members to define PK/PD endpoints and study designs. 

• Support IND-enabling strategies, including dose justification and regulatory documentation. 

• Communicate results in written and verbal form, including presentations at internal and external meetings and preparation of scientific reports.

Requirements

• Degree in pharmacometrics, pharmacokinetics, biomedical engineering, pharmaceutical sciences, applied mathematics, or related discipline. 

• PhD with 0+ years, or MS with 3+ years of experience in PK/PD modeling or pharmacometrics. 

• Hands-on experience with modeling and simulation tools such as: 

Phoenix WinNonlin, NONMEM, Monolix or similar platforms 

• Understanding of biologics PK/PD, including antibodies and/or novel modalities. 

• Language: Fluent in Korean, and professional working proficiency in English.

Statement 

Kaigene is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. 

Job type: Full-time 

We may consider supporting visa/green card application for qualified candidates.

- Contact: kh.min@kaigene.com (301-201-0010)

- Application requirement: Resume